The stress response gene ATF3 is a direct target of the Wnt/ß-catenin pathway and inhibits the invasion and migration of HCT116 human colorectal cancer cells.

Inoue, Makoto; Uchida, Yohei; Edagawa, Makoto; Hirata, Manabu; Mitamura, Jun; Miyamoto, Daiki; Taketani, Kenji; Sekine, Shigeki; Kawauchi, Junya; Kitajima, Shigetaka

Inoue, Makoto; Uchida, Yohei; Edagawa, Makoto; Hirata, Manabu; Mitamura, Jun; Miyamoto, Daiki; Taketani, Kenji; Sekine, Shigeki; Kawauchi, Junya; Kitajima, Shigetaka.

Afiliação

Inoue M; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Uchida Y; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Edagawa M; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Hirata M; Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Mitamura J; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Miyamoto D; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Taketani K; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Sekine S; Department of Biochemical Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.
Kawauchi J; Department of Surgery and Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Kitajima S; Pathology Division, National Cancer Center Research Institute, Tokyo, Japan.

PLoS One ; 13(7): e0194160, 2018.

Article em En | MEDLINE | ID: mdl-29966001

Assuntos

Fator 3 Ativador da Transcrição/genética; Biomarcadores Tumorais/genética; Carcinogênese/genética; Neoplasias Colorretais/genética; Invasividade Neoplásica/genética; Movimento Celular/genética; Proliferação de Células/genética; Neoplasias Colorretais/patologia; Regulação Neoplásica da Expressão Gênica; Células HCT116; Humanos; Metaloproteinase 2 da Matriz/genética; Metaloproteinase 9 da Matriz/genética; Invasividade Neoplásica/patologia; Ligação Proteica; Inibidor Tecidual de Metaloproteinase-3/genética; Fator de Transcrição 4/genética; Via de Sinalização Wnt/genética; beta Catenina/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Fator 3 Ativador da Transcrição / Carcinogênese / Invasividade Neoplásica Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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