Noncoding RNAs in disease.
FEBS Lett
; 592(17): 2884-2900, 2018 09.
Article
em En
| MEDLINE
| ID: mdl-29972883
Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (miRNA) (family) or a selected disease/pathology. In this Mini-Review, we highlight a selection of studies in order to demonstrate the wide-scale involvement of miRNAs and long noncoding RNAs in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
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RNA não Traduzido
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RNA Longo não Codificante
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Neoplasias
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Doenças do Sistema Nervoso
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article