Directed migration: Cells navigate by extracellular vesicles.
J Cell Biol
; 217(8): 2613-2614, 2018 08 06.
Article
em En
| MEDLINE
| ID: mdl-29976599
ABSTRACT
Directional cell motility toward a chemical gradient, chemotaxis, is critical during inflammation, embryogenesis, and cancer metastasis. In this issue, Kriebel et al. (2018. J. Cell Biol. https//doi.org/10.1083/jcb.201710170) demonstrate that the key cAMP chemoattractant for Dictyostelium discoideum amoebas is synthesized within and released from extracellular vesicles to promote chemotaxis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dictyostelium
/
Vesículas Extracelulares
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article