Spontaneous reactivation of latent HIV-1 promoters is linked to the cell cycle as revealed by a genetic-insulators-containing dual-fluorescence HIV-1-based vector.

Kok, Yik Lim; Schmutz, Stefan; Inderbitzin, Anne; Neumann, Kathrin; Kelley, Audrey; Jörimann, Lisa; Shilaih, Mohaned; Vongrad, Valentina; Kouyos, Roger D; Günthard, Huldrych F; Berens, Christian; Metzner, Karin J

Kok, Yik Lim; Schmutz, Stefan; Inderbitzin, Anne; Neumann, Kathrin; Kelley, Audrey; Jörimann, Lisa; Shilaih, Mohaned; Vongrad, Valentina; Kouyos, Roger D; Günthard, Huldrych F; Berens, Christian; Metzner, Karin J.

Afiliação

Kok YL; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Schmutz S; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Inderbitzin A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Neumann K; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Kelley A; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Jörimann L; Life Science Zurich Graduate School, University of Zurich, Zurich, Switzerland.
Shilaih M; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Vongrad V; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Kouyos RD; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.
Günthard HF; Institute of Medical Virology, University of Zurich, Zurich, Switzerland.
Berens C; Life Science Zurich Graduate School, University of Zurich, Zurich, Switzerland.
Metzner KJ; Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.

Sci Rep ; 8(1): 10204, 2018 07 05.

Article em En | MEDLINE | ID: mdl-29977044

Assuntos

Infecções por HIV/virologia; HIV-1/fisiologia; Regiões Promotoras Genéticas; Ativação Viral; Ciclo Celular; Linhagem Celular; Células Clonais/efeitos dos fármacos; Células Clonais/virologia; Genes Reporter; Genisteína/farmacologia; Infecções por HIV/genética; Humanos; Nocodazol/farmacologia; Transdução Genética; Integração Viral; Latência Viral

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ativação Viral / Infecções por HIV / HIV-1 / Regiões Promotoras Genéticas Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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