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Expression of 5T4 extracellular domain fusion protein and preparation of anti-5T4 monoclonal antibody with high affinity and internalization efficiency.
Wang, Ruixue; Lai, Qinhuai; Lu, Ying; Zhou, Yan; Tang, Liangze; Tao, Yiran; Yao, Yuqin; Yu, Lin; Liu, Yu; Wang, Yuxi; Zhang, Ruirui; Jiang, Xiaohua; Gou, Lantu; Yang, Jinliang.
Afiliação
  • Wang R; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Lai Q; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Lu Y; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Zhou Y; The Gastroenterology Tumor and Microenvironment Laboratory, Department of Gastroenterology, The First Affiliated Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu, China.
  • Tang L; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Tao Y; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Yao Y; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China; Research Center for Public Health and Preventive Medicine, West China School of Public Health and Healthy Food Evaluation Research Center, NO. 4 West China
  • Yu L; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Liu Y; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Wang Y; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Zhang R; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Jiang X; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Gou L; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
  • Yang J; Department of Biotherapy, Cancer Center/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China; Guangdong Zhongsheng Pharmaceutical Co., Ltd., China. Electronic address: jlyang01@163.com.
Protein Expr Purif ; 158: 51-58, 2019 06.
Article em En | MEDLINE | ID: mdl-29981846
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Fragmentos Fc das Imunoglobulinas / Glicoproteínas de Membrana / Anticorpos Monoclonais Murinos / Antineoplásicos Imunológicos / Afinidade de Anticorpos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Fragmentos Fc das Imunoglobulinas / Glicoproteínas de Membrana / Anticorpos Monoclonais Murinos / Antineoplásicos Imunológicos / Afinidade de Anticorpos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article