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Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells.
Satta, Alessandro; Mezzanzanica, Delia; Caroli, Francesco; Frigerio, Barbara; Di Nicola, Massimo; Kontermann, Roland E; Iacovelli, Federico; Desideri, Alessandro; Anichini, Andrea; Canevari, Silvana; Gianni, Alessandro Massimo; Figini, Mariangela.
Afiliação
  • Satta A; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Mezzanzanica D; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Caroli F; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Frigerio B; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Di Nicola M; b Medical Oncology C Unit, Department of Medical Oncology and Hematology , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Kontermann RE; c Institut for Zellbiologie und Immunologie, Universität Stuttgart , Stuttgart , Germany.
  • Iacovelli F; d Department of Biology , University of Rome Tor Vergata , Rome , Italy.
  • Desideri A; d Department of Biology , University of Rome Tor Vergata , Rome , Italy.
  • Anichini A; e Human Tumor Immunobiology Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Canevari S; a Molecular Therapies Unit, Department of Experimental Oncology and Molecular Medicine , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Gianni AM; b Medical Oncology C Unit, Department of Medical Oncology and Hematology , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.
  • Figini M; f Department of Pathophysiology and Transplantation , University of Milan , Milan , Italy.
MAbs ; 10(7): 1084-1097, 2018 10.
Article em En | MEDLINE | ID: mdl-29993310
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Anticorpos Biespecíficos / Anticorpos de Cadeia Única / Imunoterapia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T / Anticorpos Biespecíficos / Anticorpos de Cadeia Única / Imunoterapia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article