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mTOR'ing across the Cortex by Chopping the Cilia.
Di Nardo, Alessia; Sahin, Mustafa.
Afiliação
  • Di Nardo A; F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Sahin M; F.M. Kirby Neurobiology Center, Translational Neuroscience Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: mustafa.sahin@childrens.harvard.edu.
Neuron ; 99(1): 3-5, 2018 07 11.
Article em En | MEDLINE | ID: mdl-30001510
ABSTRACT
Somatic mutation of the MTOR gene is a genetic etiology of focal malformations of cortical development. In this issue of Neuron, Park et al. (2018) identify defective autophagy-dependent ciliogenesis/Wnt signaling as an underlying mechanism affecting neuronal migration and cortical lamination.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cílios / Serina-Treonina Quinases TOR Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cílios / Serina-Treonina Quinases TOR Idioma: En Ano de publicação: 2018 Tipo de documento: Article