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Plastic Scintillator-Based Microfluidic Devices for Miniaturized Detection of Positron Emission Tomography Radiopharmaceuticals.
Tarn, Mark D; Kizilyer, Nuray Yavuzkanat; Esfahani, Mohammad M N; Joshi, Pankaj; Brown, Nathaniel J; Pamme, Nicole; Jenkins, David G; Archibald, Stephen J.
Afiliação
  • Tarn MD; Positron Emission Tomography Research Centre, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
  • Kizilyer NY; School of Mathematics and Physical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
  • Esfahani MMN; Current address: School of Earth and Environment, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.
  • Joshi P; Department of Physics, University of York, Heslington, York, YO10 5DD, UK.
  • Brown NJ; Current address: Faculty of Art and Science, Bitlis Eren University, Bitlis, 13000, Turkey.
  • Pamme N; Positron Emission Tomography Research Centre, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
  • Jenkins DG; School of Engineering and Computer Science, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
  • Archibald SJ; Department of Physics, University of York, Heslington, York, YO10 5DD, UK.
Chemistry ; 24(52): 13749-13753, 2018 Sep 18.
Article em En | MEDLINE | ID: mdl-30003615
ABSTRACT
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [18 F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Guideline Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Guideline Idioma: En Ano de publicação: 2018 Tipo de documento: Article