Contributions of a regional approach to document hematologic disease in Mexico: a 10-year experience in an open population.
Hematology
; 23(10): 803-809, 2018 Dec.
Article
em En
| MEDLINE
| ID: mdl-30010502
ABSTRACT
OBJECTIVES:
To demonstrate the importance of regional efforts to register features and report frequency of hematology diseases in the context of incomplete national registries.METHODS:
Frequencies and salient characteristics of hematologic diseases in Northeast Mexico were documented in a reference center at a tertiary care university hospital during the decade 2005-2015. Disease categories were grouped by age, sex and diagnosis. Age group distribution followed WHO guidelines in years as children (0-17), adults (18-64) and elders (+65).RESULTS:
2406 patients were included 1239 (51.5%) were females and 1167 (48.5%) males; FM ratio was 1.061; median age was 35 years (0-95). The frequency by age group included adults, 1370 cases (56.9%), children, 695 cases (28.9%), and elderly, 341 (14.2%). Most frequent diagnoses were acute lymphoblastic leukemia (ALL) 18.2% (n = 438), anemia 15.9% (n = 383), non-Hodgkin's lymphoma (NHL) 15.7% (n = 378), immune thrombocytopenic purpura (ITP) 9.8% (n = 235) and Hodgkin's lymphoma (HL) 6.5% (n = 156). Median age for the whole cohort was 35 years; for children, was 6 years, for adults 40 and for the elderly 73. Results for ALL, anemia and ITP were comparable to high-income countries; NHL, HL and chronic myeloid leukemia presented a decade earlier.DISCUSSION:
Complete, opportune reliable information on the number of cases, age and sex distribution with the potential to influence strategies for timely diagnosis and treatment options for important hematologic diseases can be accrued by regional centers.CONCLUSION:
Information on hematology diseases derived of regional registries in low-middle income countries is a reasonable alternative to complement and update national registries.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sistema de Registros
/
Doenças Hematológicas
Tipo de estudo:
Guideline
/
Qualitative_research
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País como assunto:
Mexico
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article