Sero-epidemiology and Risk Factor Analysis of Measles Among Children in Pakistan.

Rasool, Muhammad Hidayat; Rafiq, Ahsan; Nawaz, Muhammad Zeeshan; Shafique, Muhammad; Saqalein, Muhammad

Rasool, Muhammad Hidayat; Rafiq, Ahsan; Nawaz, Muhammad Zeeshan; Shafique, Muhammad; Saqalein, Muhammad.

Afiliação

Rasool MH; Department of Microbiology, Government College University,Faisalabad,Pakistan.
Rafiq A; Department of Microbiology, Government College University,Faisalabad,Pakistan.
Nawaz MZ; Department of Microbiology, Government College University,Faisalabad,Pakistan.
Shafique M; Department of Microbiology, Government College University,Faisalabad,Pakistan.
Saqalein M; Department of Microbiology, Government College University,Faisalabad,Pakistan.

Pol J Microbiol ; 67(2): 227-231, 2018 Jun 30.

Article em En | MEDLINE | ID: mdl-30015462

ABSTRACT

ABSTRACT

Comparative cross sectional study was conducted on blood samples (n = 231) collected from children of 1 to 10 years of age in Punjab Pakistan through convenient sampling method. Indirect haemagglutination assay (IHA) was standardized and used for serodiagnosis and evaluation of humoral immunity against measles. Associated risk factors including age, gender, locale, and vaccination status were analyzed. Geometric mean titre (GMT) of vaccinated individuals was significantly higher (p < 0.001) than that of non-vaccinated individuals showing that IHA titre of vaccinated individuals was a measure of humoral immune response; whereas, in case of non-vaccinated individuals an indicative of exposure to the measles infection.

Assuntos

Sarampo/epidemiologia; Sarampo/imunologia; Estudos Soroepidemiológicos; Anticorpos Antivirais/sangue; Criança; Pré-Escolar; Estudos Transversais; Análise Fatorial; Feminino; Testes de Hemaglutinação; Humanos; Imunidade Humoral; Lactente; Masculino; Vírus do Sarampo; Paquistão/epidemiologia; Fatores de Risco

Palavras-chave

IHA; geometric mean titre; measles; sero-epidemiology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estudos Soroepidemiológicos / Sarampo Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male País como assunto: Asia Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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