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The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation.
Hirschler-Laszkiewicz, Iwona; Chen, Shu-Jen; Bao, Lei; Wang, JuFang; Zhang, Xue-Qian; Shanmughapriya, Santhanam; Keefer, Kerry; Madesh, Muniswamy; Cheung, Joseph Y; Miller, Barbara A.
Afiliação
  • Hirschler-Laszkiewicz I; Department of Pediatrics, The Pennsylvania State University College of Medicine , Hershey, Pennsylvania.
  • Chen SJ; Department of Pediatrics, The Pennsylvania State University College of Medicine , Hershey, Pennsylvania.
  • Bao L; Department of Pediatrics, The Pennsylvania State University College of Medicine , Hershey, Pennsylvania.
  • Wang J; The Center of Translational Medicine, Lewis Katz School of Medicine of Temple University , Philadelphia, Pennsylvania.
  • Zhang XQ; The Center of Translational Medicine, Lewis Katz School of Medicine of Temple University , Philadelphia, Pennsylvania.
  • Shanmughapriya S; The Center of Translational Medicine, Lewis Katz School of Medicine of Temple University , Philadelphia, Pennsylvania.
  • Keefer K; Department of Biochemistry, Lewis Katz School of Medicine of Temple University , Philadelphia, Pennsylvania.
  • Madesh M; Department of Pediatrics, The Pennsylvania State University College of Medicine , Hershey, Pennsylvania.
  • Cheung JY; The Center of Translational Medicine, Lewis Katz School of Medicine of Temple University , Philadelphia, Pennsylvania.
  • Miller BA; Department of Biochemistry, Lewis Katz School of Medicine of Temple University , Philadelphia, Pennsylvania.
Am J Physiol Cell Physiol ; 315(4): C571-C586, 2018 10 01.
Article em En | MEDLINE | ID: mdl-30020827

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canais de Cálcio / Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico / Quinase 2 de Adesão Focal / Canais de Cátion TRPM / Neuroblastoma Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canais de Cálcio / Proteína de Ligação ao Elemento de Resposta ao AMP Cíclico / Quinase 2 de Adesão Focal / Canais de Cátion TRPM / Neuroblastoma Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article