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Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Mandal, Pratyusha; Feng, Yanjun; Lyons, John D; Berger, Scott B; Otani, Shunsuke; DeLaney, Alexandra; Tharp, Gregory K; Maner-Smith, Kristal; Burd, Eileen M; Schaeffer, Michelle; Hoffman, Sandra; Capriotti, Carol; Roback, Linda; Young, Cedrick B; Liang, Zhe; Ortlund, Eric A; DiPaolo, Nelson C; Bosinger, Steven; Bertin, John; Gough, Peter J; Brodsky, Igor E; Coopersmith, Craig M; Shayakhmetov, Dmitry M; Mocarski, Edward S.
Afiliação
  • Mandal P; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta GA 30322, USA. Electronic address: pmanda2@emory.edu.
  • Feng Y; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Lyons JD; Department of Surgery, Emory Critical Care Center, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Berger SB; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA; Host Defense Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Otani S; Department of Surgery, Emory Critical Care Center, Emory University School of Medicine, Atlanta GA 30322, USA.
  • DeLaney A; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Tharp GK; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA.
  • Maner-Smith K; Department of Biochemistry, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Burd EM; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Schaeffer M; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Hoffman S; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA; Host Defense Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Capriotti C; Host Defense Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Roback L; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Young CB; Lowance Center for Human Immunology, Emory University, Atlanta GA 30322, USA.
  • Liang Z; Department of Surgery, Emory Critical Care Center, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Ortlund EA; Department of Biochemistry, Emory University School of Medicine, Atlanta GA 30322, USA.
  • DiPaolo NC; Lowance Center for Human Immunology, Emory University, Atlanta GA 30322, USA.
  • Bosinger S; Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA.
  • Bertin J; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Gough PJ; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA; Host Defense Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Brodsky IE; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Coopersmith CM; Department of Surgery, Emory Critical Care Center, Emory University School of Medicine, Atlanta GA 30322, USA.
  • Shayakhmetov DM; Lowance Center for Human Immunology, Emory University, Atlanta GA 30322, USA.
  • Mocarski ES; Department of Microbiology and Immunology, Emory Vaccine Center, Emory University School of Medicine, Atlanta GA 30322, USA. Electronic address: mocarski@emory.edu.
Immunity ; 49(1): 42-55.e6, 2018 07 17.
Article em En | MEDLINE | ID: mdl-30021146
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Choque Séptico / Caspases / Infecções por Escherichia coli / Caspase 8 Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Choque Séptico / Caspases / Infecções por Escherichia coli / Caspase 8 Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article