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Live rubella vectors can express native HIV envelope glycoproteins targeted by broadly neutralizing antibodies and prime the immune response to an envelope protein boost.
Virnik, Konstantin; Nesti, Edmund; Dail, Cody; Scanlan, Aaron; Medvedev, Alexei; Vassell, Russell; McGuire, Andrew T; Stamatatos, Leonidas; Berkower, Ira.
Afiliação
  • Virnik K; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA.
  • Nesti E; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA.
  • Dail C; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA.
  • Scanlan A; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA.
  • Medvedev A; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA.
  • Vassell R; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA.
  • McGuire AT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Seattle, WA, USA.
  • Stamatatos L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Global Health, University of Washington, Seattle, WA, USA.
  • Berkower I; Lab of Immunoregulation, DVP, Office of Vaccines, Center for Biologics, FDA, Bldg 72, Room 1212, White Oak Campus, 10903 New Hampshire Ave., Silver Spring, MD 20993, USA. Electronic address: Ira.berkower@fda.hhs.gov.
Vaccine ; 36(34): 5166-5172, 2018 08 16.
Article em En | MEDLINE | ID: mdl-30037665

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Rubéola / Proteína gp120 do Envelope de HIV / Infecções por HIV / Vacinas contra a AIDS / Anticorpos Neutralizantes Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus da Rubéola / Proteína gp120 do Envelope de HIV / Infecções por HIV / Vacinas contra a AIDS / Anticorpos Neutralizantes Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article