Adrenal Myelolipomas Involved by Plasma Cell Myeloma.
Am J Clin Pathol
; 150(5): 406-414, 2018 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-30052719
ABSTRACT
OBJECTIVES:
To report the presence and evaluate the frequency of plasma cell neoplasms within adrenal myelolipomas.METHODS:
Adrenal myelolipomas within our institution were reviewed for the presence of hematologic neoplasia, and a review of the literature was performed.RESULTS:
Two (9%) of 23 adrenal myelolipomas were involved by plasma cell myeloma. The patients were 71 and 81 years old, one woman and one man, with tumors measuring 7 cm and 8.5 cm, respectively. Both tumors contained large aggregates of dysplastic plasma cells occupying at least one ×10 field and demonstrated light chain restriction. Neither had an established diagnosis of plasma cell neoplasm previously. After receiving therapy, one patient exhibited a stable clinical course 1 year after diagnosis while the other died of disease 3 years later.CONCLUSIONS:
We report the first two cases of adrenal myelolipoma involved by plasma cell myeloma, a rare and subtle finding that has significant clinical implications.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mielolipoma
/
Neoplasias das Glândulas Suprarrenais
/
Neoplasias Hematológicas
/
Mieloma Múltiplo
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article