CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.

Huang, Xiaoping; Wu, Beverly P; Nguyen, Diana; Liu, Yi-Ting; Marani, Melika; Hench, Jürgen; Bénit, Paule; Kozjak-Pavlovic, Vera; Rustin, Pierre; Frank, Stephan; Narendra, Derek P

Huang, Xiaoping; Wu, Beverly P; Nguyen, Diana; Liu, Yi-Ting; Marani, Melika; Hench, Jürgen; Bénit, Paule; Kozjak-Pavlovic, Vera; Rustin, Pierre; Frank, Stephan; Narendra, Derek P.

Afiliação

Huang X; Inherited Movement Disorders Unit, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA.
Wu BP; Inherited Movement Disorders Unit, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA.
Nguyen D; Inherited Movement Disorders Unit, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA.
Liu YT; Inherited Movement Disorders Unit, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA.
Marani M; Inherited Movement Disorders Unit, Neurogenetics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD USA.
Hench J; Division of Neuropathology, Institute of Pathology, University Hospital Basel, Basel, Switzerland.
Bénit P; INSERM UMR 1141, Hôpital Robert Debré, Paris, France.
Kozjak-Pavlovic V; Department of Microbiology, Biocenter, University of Wuerzburg, Am Hubland, Wuerzburg, Germany.
Rustin P; INSERM UMR 1141, Hôpital Robert Debré, Paris, France.
Frank S; Université Paris Diderot, Paris, France.
Narendra DP; Division of Neuropathology, Institute of Pathology, University Hospital Basel, Basel, Switzerland.

Hum Mol Genet ; 27(22): 3881-3900, 2018 11 15.

Article em En | MEDLINE | ID: mdl-30084972

Assuntos

Mitocôndrias/genética; Proteínas Mitocondriais/genética; Doença de Parkinson/genética; Fatores de Transcrição/genética; Esclerose Lateral Amiotrófica/genética; Esclerose Lateral Amiotrófica/fisiopatologia; Proteínas de Ligação a DNA; Dimerização; Demência Frontotemporal/genética; Demência Frontotemporal/fisiopatologia; Células HeLa; Humanos; Potencial da Membrana Mitocondrial/genética; Mitocôndrias/patologia; Proteínas Mitocondriais/química; Mutação; Doença de Parkinson/fisiopatologia; Células Piramidais/metabolismo; Células Piramidais/patologia; Substância Negra/metabolismo; Substância Negra/patologia; Fatores de Transcrição/química

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Fatores de Transcrição / Proteínas Mitocondriais / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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