The efficacy of platelet-rich fibrin as a scaffold in regenerative endodontic treatment: a retrospective controlled cohort study.
BMC Oral Health
; 18(1): 139, 2018 08 13.
Article
em En
| MEDLINE
| ID: mdl-30103724
ABSTRACT
BACKGROUND:
Blood Clot (BC) or platelet concentrates have been used as scaffold in regenerative endodontic treatment (RET). The aim of this retrospective study was to compare the performance of platelet-rich fibrin (PRF) with BC in inducing root development and periapical lesion healing after tooth revascularization.METHODS:
Five patients receiving RET using PRF as a scaffold were matched 11 to a previous cohort of 5 patients who underwent tooth revascularization by provoking periapical bleeding. Clinical signs and symptoms were examined at follow-ups. Periapical lesion healing and root development were monitored radiographically. The resolution of clinical signs and symptoms as well as periapical radiolucency was observed in all patients (100%).RESULTS:
Root elongation, dentinal wall thickening and apex closure were found in most cases (80% in both groups). There was no significant difference between the groups in terms of clinical sign resolution, root development and periapical healing.CONCLUSIONS:
Within the limits of this study, PRF achieved comparable outcomes to BC in terms of clinical sign and symptom resolution, periapical lesion healing and continued root development in RET.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alicerces Teciduais
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Fibrina Rica em Plaquetas
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Endodontia Regenerativa
Tipo de estudo:
Etiology_studies
/
Observational_studies
Limite:
Adolescent
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Child
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article