Antibacterial Prenylated Isoflavonoids from the Stems of Millettia extensa.
J Nat Prod
; 81(8): 1835-1840, 2018 08 24.
Article
em En
| MEDLINE
| ID: mdl-30106294
ABSTRACT
The first phytochemical investigation of the stem extract of Millettia extensa resulted in the isolation and identification of six new isoflavones, millexatins A-F (1-6), together with 16 known compounds. The structures of these new compounds were determined on the basis of their spectroscopic data. Millexatin A (1) is a rare isoflavone containing three isoprenyl units on a modified A ring. Compounds 1, 6, 10, 11, and 14 displayed promising antibacterial activity with MIC values of 2-8 µg/mL.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Caules de Planta
/
Millettia
/
Isoflavonas
/
Fabaceae
/
Antibacterianos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article