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A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor.
Ye, Lintao; Ding, Kang; Zhao, Fei; Liu, Xiaoyan; Wu, Yiran; Liu, Yang; Xue, Dongxiang; Zhou, Fang; Zhang, Xianjun; Stevens, Raymond C; Xu, Fei; Zhao, Suwen; Tao, Houchao.
Afiliação
  • Ye L; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
  • Ding K; Shanghai Institute of Materia Medica , Chinese Academy of Sciences , 555 Zuchongzhi Road, Building 3, Room 426 , Shanghai , 201203 , China.
  • Zhao F; University of Chinese Academy of Sciences , No. 19A, Yuquan Road , Beijing 100049 , China.
  • Liu X; School of Life Science and Technology , ShanghaiTech University , Shanghai 201210 , China.
  • Wu Y; Key Laboratory of Computational Biology , CAS-MPG Partner Institute for Computational Biology , Shanghai Institutes for Biological Sciences , Chinese Academy of Sciences , Shanghai , 200031 , China.
  • Liu Y; University of Chinese Academy of Sciences , No. 19A, Yuquan Road , Beijing 100049 , China.
  • Xue D; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
  • Zhou F; School of Life Science and Technology , ShanghaiTech University , Shanghai 201210 , China.
  • Zhang X; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
  • Stevens RC; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
  • Xu F; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
  • Zhao S; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
  • Tao H; iHuman Institute , ShanghaiTech University , 2F Building 6, 99 Haike Road, Pudong New District , Shanghai 201210 , China . Email: zhaosw@shanghaitech.edu.cn ; Email: taohch@shanghaitech.edu.cn.
Medchemcomm ; 8(6): 1332-1336, 2017 Jun 01.
Article em En | MEDLINE | ID: mdl-30108845
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article