[Analysis of Relationship between Coagulation Function and Blood Transfusion in Patients with Emergency Rescue].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
; 26(4): 1204-1209, 2018 Aug.
Article
em Zh
| MEDLINE
| ID: mdl-30111431
ABSTRACT
OBJECTIVE:
Through researching preoperative coagulation function in the case of ABO-identical blood insufficient for emergency rescue transfusion according to recommended programs of special emergency rescue transfusion was carried out, the relationship between volume of blood products and coagulation function was analyzed.METHODS:
The surgical cases of blood transfusion more than 1 600 ml during operation were collected in our hospitals from Aug 2015 to Dec 2016ï¼n=218ï¼, these cases were divided into the normal coagulation groupï¼Group Aï¼ and abnormal coagulation groupï¼Group Bï¼, and the patients of emergency rescue transfusion O type blood groupï¼Group Cï¼. The basic information of cases, the infused volume of red blood cellï¼RBCï¼, virus-inactivated frozen plasmaï¼VIFPï¼, fresh frozen plasmaï¼FFPï¼, cryoprecipitateï¼Cï¼and plateletsï¼Pï¼, prothrombin timeï¼PTï¼, activated partial thromboplastin timeï¼APTTï¼, fibrinogenï¼FIBï¼and international normalized ratioï¼INRï¼were analyzed, the relationship between volume of blood transfusion and coagulation function were also analysed. At the same time, the efficiency and safety index were compared before and after transfusion. These indexes, such as hemoglobinï¼Hbï¼, indirect bilirubinï¼IBiLï¼, direct antiglobulin testï¼DATï¼and irregular antibody were determined at the time-paints of 24 h, 3 d and 7 d after blood transfusion.RESULTS:
The differences of age and blood type between group A and B was not statistically significantï¼P>0.05ï¼. Proportion of A and AB typeï¼transfusion volume of RBC, FFP, C and Plt all were significantly higher in group C ï¼P<0.05ï¼. PT, APTT, FIB and INR in group B and C were significantly differentï¼P<0.05ï¼, which related with the transfusion volume of RBC, FFP and Cï¼P<0.05ï¼. DAT and irregular antibody in every group was all negative before transfusion, No any new irregular antibodies had been detected after transfusion. Hb after blood transfusion was not statistically different before and after transfusion in group C, the IBiL level also was not significantly increased after blood transfusionï¼P > 0.05ï¼. All those showed that emergency rescue transfusion was safe and effective.CONCLUSION:
Preoperative coagulation function is one of factors inflnencing blood products transfusion volume during operation, which also is the basis for evaluating bleeding and blood transfusion. Emergency O type blood and ABO-matched blood transfusions show the same efficiency and safety.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Coagulação Sanguínea
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2018
Tipo de documento:
Article