Role of PKB/SGK-dependent phosphorylation of GSK-3&#945;/ß in vascular calcification during cholecalciferol overload in mice.

Tuffaha, Rashad; Voelkl, Jakob; Pieske, Burkert; Lang, Florian; Alesutan, Ioana

Role of PKB/SGK-dependent phosphorylation of GSK-3α/ß in vascular calcification during cholecalciferol overload in mice.

Tuffaha, Rashad; Voelkl, Jakob; Pieske, Burkert; Lang, Florian; Alesutan, Ioana.

Afiliação

Tuffaha R; Department of Physiology I, Eberhard-Karls University, Wilhelmstr. 56, 72076 Tübingen, Germany.
Voelkl J; Department of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Hessische Str. 3-4, 10115 Berlin, Germany. Electronic address: jakob.voe
Pieske B; Department of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Hessische Str. 3-4, 10115 Berlin, Germany; Berlin Institute of Health (B
Lang F; Department of Physiology I, Eberhard-Karls University, Wilhelmstr. 56, 72076 Tübingen, Germany.
Alesutan I; Department of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Hessische Str. 3-4, 10115 Berlin, Germany; Berlin Institute of Health (B

Biochem Biophys Res Commun ; 503(3): 2068-2074, 2018 09 10.

Article em En | MEDLINE | ID: mdl-30119888

Assuntos

Colecalciferol/metabolismo; Glicogênio Sintase Quinase 3 beta/metabolismo; Quinase 3 da Glicogênio Sintase/metabolismo; Proteínas Imediatamente Precoces/metabolismo; Proteínas Serina-Treonina Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Calcificação Vascular/metabolismo; Animais; Colecalciferol/administração & dosagem; Quinase 3 da Glicogênio Sintase/deficiência; Glicogênio Sintase Quinase 3 beta/deficiência; Injeções Subcutâneas; Camundongos; Camundongos Knockout; Fosforilação

Palavras-chave

Glycogen synthase kinase 3; Osteogenic signaling; Protein kinase B; Serum- and glucocorticoid-inducible kinase; Vascular calcification

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Proteínas Imediatamente Precoces / Colecalciferol / Quinase 3 da Glicogênio Sintase / Proteínas Proto-Oncogênicas c-akt / Calcificação Vascular / Glicogênio Sintase Quinase 3 beta Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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