Expression of the inhibitory B7 family molecule VISTA in human colorectal carcinoma tumors.

Xie, Shan; Huang, Jia; Qiao, Qin; Zang, Wenjuan; Hong, Shanjuan; Tan, Haidong; Dong, Chen; Yang, Zhiying; Ni, Ling

Xie, Shan; Huang, Jia; Qiao, Qin; Zang, Wenjuan; Hong, Shanjuan; Tan, Haidong; Dong, Chen; Yang, Zhiying; Ni, Ling.

Afiliação

Xie S; Institute for Immunology and School of Medicine, Tsinghua University, Medical Research Building, No.30 Haidian Shuangqing Road, Beijing, 100084, China.
Huang J; Department of General Surgery, China-Japan Friendship Hospital, Beijing, 100029, China.
Qiao Q; Institute for Immunology and School of Medicine, Tsinghua University, Medical Research Building, No.30 Haidian Shuangqing Road, Beijing, 100084, China.
Zang W; Institute for Immunology and School of Medicine, Tsinghua University, Medical Research Building, No.30 Haidian Shuangqing Road, Beijing, 100084, China.
Hong S; Institute for Immunology and School of Medicine, Tsinghua University, Medical Research Building, No.30 Haidian Shuangqing Road, Beijing, 100084, China.
Tan H; Department of General Surgery, China-Japan Friendship Hospital, Beijing, 100029, China.
Dong C; Institute for Immunology and School of Medicine, Tsinghua University, Medical Research Building, No.30 Haidian Shuangqing Road, Beijing, 100084, China.
Yang Z; Department of General Surgery, China-Japan Friendship Hospital, Beijing, 100029, China. yangzhy@aliyun.com.
Ni L; Institute for Immunology and School of Medicine, Tsinghua University, Medical Research Building, No.30 Haidian Shuangqing Road, Beijing, 100084, China. lingni@tsinghua.edu.cn.

Cancer Immunol Immunother ; 67(11): 1685-1694, 2018 Nov.

Article em En | MEDLINE | ID: mdl-30128738

Assuntos

Antígenos B7/metabolismo; Antígeno B7-H1/metabolismo; Biomarcadores Tumorais/metabolismo; Neoplasias Colorretais/patologia; Linfócitos do Interstício Tumoral/imunologia; Evasão Tumoral/imunologia; Idoso; Idoso de 80 Anos ou mais; Antígenos B7/genética; Antígeno B7-H1/genética; Biomarcadores Tumorais/genética; Estudos de Casos e Controles; Neoplasias Colorretais/imunologia; Neoplasias Colorretais/metabolismo; Feminino; Seguimentos; Humanos; Linfócitos do Interstício Tumoral/metabolismo; Masculino; Pessoa de Meia-Idade; Prognóstico; Taxa de Sobrevida; Microambiente Tumoral

Palavras-chave

Immune checkpoint; Immunotherapy; PD-L1; Tumor immunity; VISTA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Linfócitos do Interstício Tumoral / Evasão Tumoral / Antígenos B7 / Antígeno B7-H1 Tipo de estudo: Observational_studies / Prognostic_studies Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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