The metabolic and molecular mechanisms of hyperammonaemia- and hyperethanolaemia-induced protein catabolism in skeletal muscle cells.

Crossland, Hannah; Smith, Kenneth; Atherton, Philip J; Wilkinson, Daniel J

Crossland, Hannah; Smith, Kenneth; Atherton, Philip J; Wilkinson, Daniel J.

Afiliação

Crossland H; MRC-ARUK Centre for Musculoskeletal Ageing Research, NIHR Biomedical Research Centre, Clinical, Metabolic and Molecular Physiology, Division of Medical Sciences and Graduate Entry Medicine, Royal Derby Hospital, School of Medicine, University of Nottingham, Derby, UK.
Smith K; MRC-ARUK Centre for Musculoskeletal Ageing Research, NIHR Biomedical Research Centre, Clinical, Metabolic and Molecular Physiology, Division of Medical Sciences and Graduate Entry Medicine, Royal Derby Hospital, School of Medicine, University of Nottingham, Derby, UK.
Atherton PJ; MRC-ARUK Centre for Musculoskeletal Ageing Research, NIHR Biomedical Research Centre, Clinical, Metabolic and Molecular Physiology, Division of Medical Sciences and Graduate Entry Medicine, Royal Derby Hospital, School of Medicine, University of Nottingham, Derby, UK.
Wilkinson DJ; MRC-ARUK Centre for Musculoskeletal Ageing Research, NIHR Biomedical Research Centre, Clinical, Metabolic and Molecular Physiology, Division of Medical Sciences and Graduate Entry Medicine, Royal Derby Hospital, School of Medicine, University of Nottingham, Derby, UK.

J Cell Physiol ; 233(12): 9663-9673, 2018 12.

Article em En | MEDLINE | ID: mdl-30144060

Assuntos

Etanol/sangue; Hiperamonemia/metabolismo; Células Musculares/metabolismo; Proteínas Musculares/metabolismo; Músculo Esquelético/metabolismo; Amônia/toxicidade; Animais; Linhagem Celular; Sobrevivência Celular/efeitos dos fármacos; DNA/metabolismo; Etanol/toxicidade; Camundongos; Fosforilação/efeitos dos fármacos; Biossíntese de Proteínas/efeitos dos fármacos; RNA/metabolismo; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

hyperammonaemia; protein catabolism; skeletal muscle

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Músculo Esquelético / Hiperamonemia / Células Musculares / Etanol / Proteínas Musculares Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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