Is there a link between periampullary diverticula and biliopancreatic disease? An EUS approach to answer the question.
Dig Liver Dis
; 50(9): 925-930, 2018 Sep.
Article
em En
| MEDLINE
| ID: mdl-30145052
ABSTRACT
BACKGROUND:
Many studies, almost all in an Endoscopic Retrograde Cholangiopancreatography (ERCP) setting, have been conducted to establish if a link exists between periampullary diverticula (PADs) and biliopancreatic diseases but the issue is still debated.AIMS:
The objective was to clarify the link between PADs and biliopancreatic disease, for the first time using Endoscopic Ultrasound (EUS).METHODS:
We retrospectively reviewed our database seeking patients scheduled for EUS with an indication that entailed the exploration of the second duodenum. For each patient with a PAD enrolled in the study, 6 controls were randomly selected.RESULTS:
2475 patients met the inclusion criteria. Among them, 185 subjects with a PAD were found (prevalence 7.5%), 1110 subjects served as controls. Patients with a PAD had more frequently a history of cholangitis (8.1 vs 2.2%; OR 3.99, pâ¯<â¯0.001), a higher prevalence of common bile duct (CBD) dilation (44.3 vs 28.2%; OR 2, pâ¯<â¯0.0001) and a higher prevalence of CBD stones (34.1 vs 19.6%; OR 2.1, pâ¯<â¯0.0001). No differences were found about history of jaundice, acute/recurrent pancreatitis or EUS signs of chronic pancreatitis.CONCLUSION:
Whereas PADs were linked with history of cholangitis, CBD stones and dilation, no association was found with pancreatic diseases.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Pancreatopatias
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Doenças Biliares
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Divertículo
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Endossonografia
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Duodenopatias
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article