Directed OmniChange Evolution Converts P450 BM3 into an Alkyltrimethylammonium Hydroxylase.

Ji, Yu; Mertens, Alan Maurice; Gertler, Christoph; Fekiri, Sallama; Keser, Merve; Sauer, Daniel F; Smith, Kilian E C; Schwaneberg, Ulrich.

Afiliação

Ji Y; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
Mertens AM; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
Gertler C; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
Fekiri S; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
Keser M; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
Sauer DF; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
Smith KEC; Institute for Environmental Research, RWTH Aachen University, Worringerweg 1, 52074, Aachen, Germany.
Schwaneberg U; Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.

Chemistry ; 24(63): 16865-16872, 2018 Nov 13.

Article em En | MEDLINE | ID: mdl-30151933