Generalized basaloid follicular hamartoma syndrome versus Gorlin syndrome: A diagnostic challenge.
Pediatr Dermatol
; 35(6): e396-e397, 2018 Nov.
Article
em En
| MEDLINE
| ID: mdl-30152544
ABSTRACT
Basaloid follicular hamartoma is a relatively rare benign neoplasm of follicular origin that can be mistaken histologically for basal cell carcinoma, but hereditary forms of basaloid follicular hamartoma are associated with nevoid basal cell carcinoma syndrome, or Gorlin syndrome. The pathophysiology of basaloid follicular hamartoma development involves mutations in the patched gene, which is also causative in nevoid basal cell carcinoma syndrome. We present a mother and daughter with basaloid follicular hamartomas, with genetic testing confirming patched gene mutation in the daughter.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dermatopatias Genéticas
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Neoplasias Cutâneas
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Síndrome do Nevo Basocelular
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Folículo Piloso
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Hamartoma
Tipo de estudo:
Diagnostic_studies
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Prognostic_studies
Limite:
Adult
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Female
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Humans
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Infant
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article