Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness.

Nwogu, Nnenna; Boyne, James R; Dobson, Samuel J; Poterlowicz, Krzysztof; Blair, G Eric; Macdonald, Andrew; Mankouri, Jamel; Whitehouse, Adrian

Nwogu, Nnenna; Boyne, James R; Dobson, Samuel J; Poterlowicz, Krzysztof; Blair, G Eric; Macdonald, Andrew; Mankouri, Jamel; Whitehouse, Adrian.

Afiliação

Nwogu N; School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Boyne JR; Centre for Skin Sciences, School of Chemistry and Biosciences, Faculty of Life Sciences, University of Bradford, Bradford, United Kingdom.
Dobson SJ; School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Poterlowicz K; Centre for Skin Sciences, School of Chemistry and Biosciences, Faculty of Life Sciences, University of Bradford, Bradford, United Kingdom.
Blair GE; School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Macdonald A; School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Mankouri J; School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Whitehouse A; School of Molecular and Cellular Biology and Astbury Centre for Structural Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.

PLoS Pathog ; 14(9): e1007276, 2018 09.

Article em En | MEDLINE | ID: mdl-30188954

Assuntos

Antígenos Virais de Tumores/fisiologia; Carcinoma de Célula de Merkel/etiologia; Poliomavírus das Células de Merkel/patogenicidade; Infecções por Polyomavirus/etiologia; Neoplasias Cutâneas/etiologia; Infecções Tumorais por Vírus/etiologia; Proteína ADAM10/metabolismo; Proteína ADAM17/metabolismo; Secretases da Proteína Precursora do Amiloide/metabolismo; Carcinoma de Célula de Merkel/enzimologia; Carcinoma de Célula de Merkel/secundário; Movimento Celular; Células HEK293; Humanos; Junções Intercelulares/patologia; Junções Intercelulares/fisiologia; Proteínas de Membrana/metabolismo; Poliomavírus das Células de Merkel/imunologia; Poliomavírus das Células de Merkel/fisiologia; Invasividade Neoplásica/patologia; Invasividade Neoplásica/fisiopatologia; Infecções por Polyomavirus/enzimologia; Infecções por Polyomavirus/patologia; Neoplasias Cutâneas/enzimologia; Neoplasias Cutâneas/patologia; Infecções Tumorais por Vírus/enzimologia; Infecções Tumorais por Vírus/patologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Infecções Tumorais por Vírus / Carcinoma de Célula de Merkel / Infecções por Polyomavirus / Poliomavírus das Células de Merkel / Antígenos Virais de Tumores Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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