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A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action.
Wong, Shi Quan; Jones, Alistair; Dodd, Steven; Grimes, Douglas; Barclay, Jeff W; Marson, Anthony G; Cunliffe, Vincent T; Burgoyne, Robert D; Sills, Graeme J; Morgan, Alan.
Afiliação
  • Wong SQ; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: wongsq@liverpool.ac.uk.
  • Jones A; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: Alistair.Jones@liverpool.ac.uk.
  • Dodd S; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: stedodd@liverpool.ac.uk.
  • Grimes D; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: hldgrime@liverpool.ac.uk.
  • Barclay JW; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: barclayj@liverpool.ac.uk.
  • Marson AG; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: marjon01@liverpool.ac.uk.
  • Cunliffe VT; Department of Biomedical Science, University of Sheffield, Sheffield, UK. Electronic address: v.t.cunliffe@sheffield.ac.uk.
  • Burgoyne RD; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: burgoyne@liverpool.ac.uk.
  • Sills GJ; Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: g.sills@liverpool.ac.uk.
  • Morgan A; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: amorgan@liverpool.ac.uk.
J Neurosci Methods ; 309: 132-142, 2018 11 01.
Article em En | MEDLINE | ID: mdl-30189284
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Modelos Animais de Doenças / Avaliação Pré-Clínica de Medicamentos / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Convulsões / Modelos Animais de Doenças / Avaliação Pré-Clínica de Medicamentos / Anticonvulsivantes Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article