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Synthesis of ß-Alkyl 2-Hydroxychalcones by Rhodium-Catalyzed Coupling of N-Phenoxyacetamides and Nonterminal Propargyl Alcohols.
Zhou, Wei; Mei, Yan-Le; Li, Bin; Guan, Zhen-Yu; Deng, Qing-Hai.
Afiliação
  • Zhou W; The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials , Shanghai Normal University , Shanghai 200234 , P. R. China.
  • Mei YL; The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials , Shanghai Normal University , Shanghai 200234 , P. R. China.
  • Li B; The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials , Shanghai Normal University , Shanghai 200234 , P. R. China.
  • Guan ZY; The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials , Shanghai Normal University , Shanghai 200234 , P. R. China.
  • Deng QH; The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials , Shanghai Normal University , Shanghai 200234 , P. R. China.
Org Lett ; 20(18): 5808-5812, 2018 09 21.
Article em En | MEDLINE | ID: mdl-30192152
An efficient rhodium-catalyzed coupling of N-phenoxyacetamides and nonterminal propargyl alcohols has been developed. A series of ß-Alkyl 2-hydroxychalcones bearing diverse functional groups were obtained with excellent regio- and stereoselectivity, and the desired chalcones could then be converted to triazole and chromene smoothly.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article