Synthesis of ß-Alkyl 2-Hydroxychalcones by Rhodium-Catalyzed Coupling of N-Phenoxyacetamides and Nonterminal Propargyl Alcohols.
Org Lett
; 20(18): 5808-5812, 2018 09 21.
Article
em En
| MEDLINE
| ID: mdl-30192152
An efficient rhodium-catalyzed coupling of N-phenoxyacetamides and nonterminal propargyl alcohols has been developed. A series of ß-Alkyl 2-hydroxychalcones bearing diverse functional groups were obtained with excellent regio- and stereoselectivity, and the desired chalcones could then be converted to triazole and chromene smoothly.
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MEDLINE
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En
Ano de publicação:
2018
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Article