Development of a skin-friendly microemulsion for dermal allergen-specific immunotherapy.

Kiselmann, C; Dobler, D; Schmidts, T; Eicher, A C; Möbs, C; Pfützner, W; Runkel, F

Kiselmann, C; Dobler, D; Schmidts, T; Eicher, A C; Möbs, C; Pfützner, W; Runkel, F.

Afiliação

Kiselmann C; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen - University of Applied Sciences, Wiesenstraße 14, 35390 Giessen, Germany. Electronic address: christopher.kiselmann@lse.thm.de.
Dobler D; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen - University of Applied Sciences, Wiesenstraße 14, 35390 Giessen, Germany.
Schmidts T; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen - University of Applied Sciences, Wiesenstraße 14, 35390 Giessen, Germany.
Eicher AC; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen - University of Applied Sciences, Wiesenstraße 14, 35390 Giessen, Germany.
Möbs C; Clinical & Experimental Allergology, Department of Dermatology and Allergology, Philipps University Marburg, Baldingerstraße, 35043 Marburg, Germany.
Pfützner W; Clinical & Experimental Allergology, Department of Dermatology and Allergology, Philipps University Marburg, Baldingerstraße, 35043 Marburg, Germany.
Runkel F; Institute of Bioprocess Engineering and Pharmaceutical Technology, Technische Hochschule Mittelhessen - University of Applied Sciences, Wiesenstraße 14, 35390 Giessen, Germany; Faculty of Biology and Chemistry, Justus Liebig University, Ludwigstraße 23, 35390 Giessen, Germany.

Int J Pharm ; 550(1-2): 463-469, 2018 Oct 25.

Article em En | MEDLINE | ID: mdl-30194011

Assuntos

Alérgenos/administração & dosagem; Dessensibilização Imunológica; Pele/metabolismo; Administração Cutânea; Animais; Carbocianinas/administração & dosagem; Emulsões; Corantes Fluorescentes/administração & dosagem; Hipersensibilidade/terapia; Camundongos; Conservantes Farmacêuticos/administração & dosagem; Absorção Cutânea; Suínos

Palavras-chave

Allergen-specific immunotherapy; Api m 1; Bee-venom phospholipase A2; Microemulsion; Skin penetration; Transdermal immunotherapy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pele / Alérgenos / Dessensibilização Imunológica Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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