The relationship between echocardiographic epicardial adipose tissue, P-wave dispersion, and corrected QT interval.
Turk Kardiyol Dern Ars
; 46(6): 471-478, 2018 09.
Article
em En
| MEDLINE
| ID: mdl-30204138
ABSTRACT
OBJECTIVE:
Epicardial adipose tissue (EAT) secretes various pro-inflammatory and atherogenic substances that have several effects on the heart. The goal of this study was to evaluate the association between EAT thickness and both P-wave dispersion (Pd) and corrected QT interval (QTc), as simple, non-invasive indicators of arrhythmia on a surface electrocardiogram.METHODS:
This retrospective observational study included 216 patients who had normal coronary arteries observed on coronary angiography. Each patient underwent 12-derivation electrocardiography to measure Pd and QTc, and transthoracic echocardiography to measure EAT thickness. The patients were divided into 2 groups according to the median EAT value (EAT low group <5.35 mm; EAT high group ≥5.35 mm).RESULTS:
P-wave dispersion (p=0.001) was significantly greater in the EAT high group compared with the EAT low group. However, the QTc (p=0.004) was significantly greater in the latter group. The median left ventricular end-diastolic diameter (p=0.033), mean left ventricular end-systolic diameter (p=0.039), and mean left atrial diameter (p=0.012) were significantly greater in the EAT high group. Multiple logistic regression analysis using the backward elimination method revealed that the leukocyte count (Odds ratio [OR] 1.000; 95% confidence interval [CI] 1.000-1.000; p=0.001), Pd (OR 1.1026; 95% CI 1.010-1.043; p=0.002), QTc interval (OR 0.988; 95% CI 0.979-0.997; p=0.009), and left ventricular ejection fraction (OR 0.922; 95% CI 0.859-0.989; p=0.023) were independently associated with greater EAT thickness.CONCLUSION:
Echocardiographic end-diastolic EAT thickness on the free wall of the right ventricle was associated with Pd and QTc in patients with normal coronary arteries.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pericárdio
/
Arritmias Cardíacas
/
Tecido Adiposo
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article