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Effects of age and genetic variations in VKORC1, CYP2C9 and CYP3A4 on the phenprocoumon dose in pediatric patients.
Maagdenberg, Hedy; Bierings, Marc B; van Ommen, C Heleen; van der Meer, Felix Jm; Appel, Inge M; Tamminga, Rienk Yj; Cessie, Saskia le; Swen, Jesse J; der Straaten, Tahar van; Boer, Anthonius de; Maitland-van der Zee, Anke H.
Afiliação
  • Maagdenberg H; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
  • Bierings MB; Department of Pediatric Stem Cell Transplantation, Princess Maxima Center for pediatric oncology/Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
  • van Ommen CH; Department of Pediatric Oncology/Hematology, Erasmus MC/Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van der Meer FJ; Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.
  • Appel IM; Department of Pediatric Oncology/Hematology, Erasmus MC/Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Tamminga RY; Department of Pediatric Hematology, University Medical Center Groningen, Groningen, The Netherlands.
  • Cessie SL; Department of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.
  • Swen JJ; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
  • der Straaten TV; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
  • Boer A; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
  • Maitland-van der Zee AH; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Pharmacogenomics ; 19(15): 1195-1202, 2018 10.
Article em En | MEDLINE | ID: mdl-30207196
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Femprocumona / Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP3A / Vitamina K Epóxido Redutases / Citocromo P-450 CYP2C9 / Anticoagulantes Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Femprocumona / Polimorfismo de Nucleotídeo Único / Citocromo P-450 CYP3A / Vitamina K Epóxido Redutases / Citocromo P-450 CYP2C9 / Anticoagulantes Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article