The Assessment of Serum Endocan Levels in Children With Juvenile Idiopathic Arthritis.
Arch Rheumatol
; 33(2): 168-173, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-30207559
ABSTRACT
OBJECTIVES:
This study aims to evaluate the levels of serum endocan in children with juvenile idiopathic arthritis (JIA). PATIENTS ANDMETHODS:
Sixty-seven children with JIA (30 males, 37 females; mean age 10.4±4.9 years; range 2 to 18 years) and a sex- and age- matched healthy control group of 39 children (16 males, 23 females; mean age 9.3±4.1 years; range 1 to 17 years) were recruited. Patients with JIA were divided into two groups as the clinically active JIA group (n=27) and inactive JIA group (n=40).RESULTS:
The median serum endocan level in patients with JIA was significantly higher than in the control group (633.75 ng/L vs. 379.76 ng/L, p<0.01). Comparison between patients with active JIA and inactive JIA was not significant in terms of endocan levels (618.70 ng/L vs. 687.36 ng/L, p=0.34). There was a weak negative correlation between Childhood Health Assessment Questionnaire scores of patients with JIA and serum endocan levels.CONCLUSION:
The high level of serum endocan highlighted the endothelial damage in patients with JIA.
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MEDLINE
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article