Disparity of access to kidney transplantation by Indigenous and non-Indigenous Australians.
Med J Aust
; 209(6): 261-266, 2018 09 17.
Article
em En
| MEDLINE
| ID: mdl-30208818
ABSTRACT
OBJECTIVE:
To compare the likelihood of Indigenous and non-Indigenous Australians being placed on the waiting list for transplantation of a kidney from a deceased donor; to compare the subsequent likelihood of transplantation. DESIGN, SETTING ANDPARTICIPANTS:
Observational cohort study; analysis of data from the Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry for patients aged 18-60 years at the start of renal replacement therapy, who commenced renal replacement therapy in Australia between 28 June 2006 and 31 December 2016. MAIN OUTCOMEMEASURES:
Time to wait-listing; time to kidney transplantation after wait-listing.RESULTS:
10 839 patients met the inclusion criteria, of whom 2039 (19%) were Indigenous Australians; 217 Indigenous and 3829 non-Indigenous patients were active on the waiting list at least once during the study period. The hazard ratio (HR) for wait-listing (Indigenous v non-Indigenous patients, adjusted for patient- and disease-related factors) in the first year of renal replacement therapy varied with age and remoteness (range, 0.11 [95% CI, 0.07-0.15] to 0.36 [95% CI, 0.16-0.56]); in subsequent years the adjusted HR was 0.90 (95% CI, 0.50-1.6). The adjusted HR for transplantation during the first year of wait-listing did not differ significantly from 1.0; for subsequent years of wait-listing, however, the adjusted HR was 0.40 (95% CI, 0.29-0.55).CONCLUSION:
Disparities between Indigenous and non-Indigenous patients with end-stage kidney disease in access to kidney transplantation are not explained by patient- or disease-related factors. Changes in policy and practice are needed to reduce these differences.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Transplante de Rim
/
Havaiano Nativo ou Outro Ilhéu do Pacífico
/
Acessibilidade aos Serviços de Saúde
/
Falência Renal Crônica
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País como assunto:
Oceania
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article