Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor <i>CDKN1A</i> in colon cancer cells.

Gerecke, Christian; Schumacher, Fabian; Edlich, Alexander; Wetzel, Alexandra; Yealland, Guy; Neubert, Lena Katharina; Scholtka, Bettina; Homann, Thomas; Kleuser, Burkhard

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells.

Gerecke, Christian; Schumacher, Fabian; Edlich, Alexander; Wetzel, Alexandra; Yealland, Guy; Neubert, Lena Katharina; Scholtka, Bettina; Homann, Thomas; Kleuser, Burkhard.

Afiliação

Gerecke C; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Schumacher F; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Edlich A; Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.
Wetzel A; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Yealland G; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Neubert LK; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Scholtka B; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Homann T; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.
Kleuser B; Institute of Nutritional Science, Department of Nutritional Toxicology, University of Potsdam, Nuthetal, Germany.