Functional exercise capacity evaluated by timed walk tests in myasthenia gravis.
Muscle Nerve
; 59(2): 208-212, 2019 02.
Article
em En
| MEDLINE
| ID: mdl-30230561
ABSTRACT
INTRODUCTION:
We sought to evaluate the test-retest reliability and construct validity of the 6- and 2-minute walk tests (6mWT and 2mWT, respectively) in patients with myasthenia gravis (MG).METHODS:
Thirty-one patients with generalized MG were enrolled in this study. The 6mWT, 2mWT, MG-specific quality of life questionnaire Turkish version (MG-QoL15T), quantitative myasthenia gravis test (QMG), and pulmonary function tests were administered.RESULTS:
The intraclass correlation coefficients of 2mWT and 6mWT were 0.894 and 0.932, respectively. The 6mWT and 2mWT had moderate correlations with forced vital capacity, maximal inspiratory pressure, QMG score, and MG-QoL15T score (ρ for 6mWT 0.579, 0.539, -0.572, and -0.474; ρ for 2mWT 0.460, 0.446, -0.532, -0.457). Both tests had similar performances for predicting disease severity (area under the curve = 0.761 for 6mWT and 0.759 for 2mWT).DISCUSSION:
The 6mWT and 2mWT have excellent test-retest reliability as well as moderate construct validity for the evaluation of functional exercise capacity patients with MG. Muscle Nerve 59208-212, 2019.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Tolerância ao Exercício
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Teste de Caminhada
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Miastenia Gravis
Tipo de estudo:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País como assunto:
Asia
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article