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Hypercalcemia and cancer: Differential diagnosis and treatment.
Zagzag, Jonathan; Hu, Mimi I; Fisher, Sarah B; Perrier, Nancy D.
Afiliação
  • Zagzag J; Fellow, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Hu MI; Associate Professor, Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Fisher SB; Fellow, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Perrier ND; Professor, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
CA Cancer J Clin ; 68(5): 377-386, 2018 09.
Article em En | MEDLINE | ID: mdl-30240520
Incidentally detected hypercalcemia usually presents in an indolent manner and is most likely caused by primary hyperparathyroidism. In contrast, hypercalcemia in the patient with a history of cancer presents in a wide range of clinical settings and may be severe enough to warrant hospitalization. This form of hypercalcemia is usually secondary to hypercalcemia of malignancy and can be fatal. Hypercalcemia of malignancy is most commonly mediated by tumoral production of parathyroid hormone-related protein or by cytokines activating osteoclast degradation of bone. The initial workup, differential diagnoses, confirmatory laboratory testing, imaging, and medical and surgical management of hypercalcemia are described in the patient with cancer.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Hipercalcemia / Melanoma Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Hipercalcemia / Melanoma Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article