ADAM17, A disintegrin and metalloprotease domain-containing protein 17; AFP, Alpha-fetoprotein; AKT, AKT/Protein kinase B; ALP, Alkaline phosphatase; ALT, Alanine aminotransferase; ANOVA, Analysis of variance; API-5, Apoptosis inhibitor-5; AST, Aspartate aminotransferase; AUC, Area under the curve; BCLC, Barcelona Clinic Liver Cancer; Bcl-2, B cell leukemia/lymphoma 2 like protein; CT, Computed tomography; CTP, Child-Turcotte-Pugh; Ccgn1, Cyclin G1 protein; Ct, Cycle threshold; Diagnosis; ELISA, Enzyme-linked immunosorbent assay; HCC, Hepatocellular carcinoma; HCV, Hepatitis C virus; Hepatocellular carcinoma; NF-κß, nuclear factor kappa-light-chain-enhancer of activated B cells; PCR, Polymerase chain reaction; RNA, Ribonucleic acid; ROC, Receiver operating characteristic; RQ, Relative quantity; SE, standard error; Sensitivity; has-miR-122, Homo sapien-micro RNA-122; mRNA, Messenger RNA; miR-122; miR-224; miRNA/miR, Micro-RNA