Immunogenic cell death of dendritic cells following modified vaccinia virus Ankara infection enhances CD8<sup>+</sup> T cell proliferation.

Tappe, Kim A; Budida, Ramachandramouli; Stankov, Metodi V; Frenz, Theresa; R Shah, Harshit; Volz, Asisa; Sutter, Gerd; Kalinke, Ulrich; Behrens, Georg M N

Immunogenic cell death of dendritic cells following modified vaccinia virus Ankara infection enhances CD8⁺ T cell proliferation.

Tappe, Kim A; Budida, Ramachandramouli; Stankov, Metodi V; Frenz, Theresa; R Shah, Harshit; Volz, Asisa; Sutter, Gerd; Kalinke, Ulrich; Behrens, Georg M N.

Afiliação

Tappe KA; Department for Clinical Immunology and Rheumatology, Hanover Medical School, Hanover, Germany.
Budida R; Department for Clinical Immunology and Rheumatology, Hanover Medical School, Hanover, Germany.
Stankov MV; Department for Clinical Immunology and Rheumatology, Hanover Medical School, Hanover, Germany.
Frenz T; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hanover Medical School and the Helmholtz Centre for Infection Research, Hanover, Germany.
R Shah H; Department for Clinical Immunology and Rheumatology, Hanover Medical School, Hanover, Germany.
Volz A; German Center for Infection Research (DZIF), partner site Munich, Germany.
Sutter G; Institute for Infectious Diseases and Zoonoses, Ludwig Maximilian University of Munich, Munich, Germany.
Kalinke U; German Center for Infection Research (DZIF), partner site Munich, Germany.
Behrens GMN; Institute for Infectious Diseases and Zoonoses, Ludwig Maximilian University of Munich, Munich, Germany.

Eur J Immunol ; 48(12): 2042-2054, 2018 12.

Article em En | MEDLINE | ID: mdl-30259962

Assuntos

Linfócitos T CD8-Positivos/imunologia; Células Dendríticas/imunologia; Varíola/imunologia; Vaccinia virus/imunologia; Vacinas Virais/imunologia; Imunidade Adaptativa; Trifosfato de Adenosina/imunologia; Trifosfato de Adenosina/metabolismo; Animais; Autofagia; Células da Medula Óssea/imunologia; Morte Celular; Proliferação de Células; Células Cultivadas; Apresentação Cruzada; Citotoxicidade Imunológica; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Receptores Purinérgicos P2X7/metabolismo; Vacinas de DNA

Palavras-chave

ATP secretion; autophagy; dendritic cells; immunogenic cell death; modified vaccinia virus Ankara (MVA)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vaccinia virus / Células Dendríticas / Varíola / Vacinas Virais / Linfócitos T CD8-Positivos Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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