Sub-acute intravenous exposure to Fe<sub>2</sub>O<sub>3</sub> nanoparticles does not alter cognitive performances and catecholamine levels, but slightly disrupts plasma iron level and brain iron content in rats.

Askri, Dalel; Ouni, Souhir; Galai, Said; Chovelon, Benoit; Arnaud, Josiane; Lehmann, Sylvia G; Sakly, Mohsen; Sève, Michel; Amara, Salem

Sub-acute intravenous exposure to Fe₂O₃ nanoparticles does not alter cognitive performances and catecholamine levels, but slightly disrupts plasma iron level and brain iron content in rats.

Askri, Dalel; Ouni, Souhir; Galai, Said; Chovelon, Benoit; Arnaud, Josiane; Lehmann, Sylvia G; Sakly, Mohsen; Sève, Michel; Amara, Salem.

Afiliação

Askri D; Univ. Grenoble Alpes, CHU Grenoble Alpes, Grenoble, PROMETHEE Proteomic Platform, 38000 Grenoble, France; Univ. Carthage, Fac. Sciences of Bizerte, Unit of Research in Integrated Physiology, Bizerte, Tunisia; Univ. Grenoble Alpes, Inserm, LBFA, BEeSy, 38000 Grenoble, France. Electronic address: dale
Ouni S; Univ. Carthage, Fac. Sciences of Bizerte, Unit of Research in Integrated Physiology, Bizerte, Tunisia.
Galai S; University of Tunis El Manar, Laboratory of Clinical Biology, National Institute of Neurology, Tunis, Tunisia.
Chovelon B; CHU Grenoble Alpes, Unit of Hormonal and Nutritional Biochemistry, Institute of Biology and Pathology, F 38000 Grenoble, France.
Arnaud J; Univ. Grenoble Alpes, Inserm, LBFA, BEeSy, 38000 Grenoble, France; CHU Grenoble Alpes, Unit of Hormonal and Nutritional Biochemistry, Institute of Biology and Pathology, F 38000 Grenoble, France.
Lehmann SG; Univ. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, IRD, IFSTTAR, ISTerre, 38000 Grenoble, France.
Sakly M; Univ. Carthage, Fac. Sciences of Bizerte, Unit of Research in Integrated Physiology, Bizerte, Tunisia.
Sève M; Univ. Grenoble Alpes, CHU Grenoble Alpes, Grenoble, PROMETHEE Proteomic Platform, 38000 Grenoble, France; Univ. Grenoble Alpes, Inserm, LBFA, BEeSy, 38000 Grenoble, France.
Amara S; Univ. Carthage, Fac. Sciences of Bizerte, Unit of Research in Integrated Physiology, Bizerte, Tunisia.

J Trace Elem Med Biol ; 50: 73-79, 2018 Dec.

Article em En | MEDLINE | ID: mdl-30262319

Assuntos

Catecolaminas/metabolismo; Cognição/efeitos dos fármacos; Compostos Férricos/efeitos adversos; Compostos Férricos/química; Ferro/sangue; Ferro/metabolismo; Nanopartículas Metálicas/efeitos adversos; Animais; Encéfalo/metabolismo; Cromatografia Líquida de Alta Pressão; Fígado/metabolismo; Masculino; Aprendizagem em Labirinto/efeitos dos fármacos; Ratos; Ratos Wistar

Palavras-chave

Catecholamines; Cognition; Fe(2)O(3-)NPs; Iron; Rat

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Férricos / Catecolaminas / Cognição / Nanopartículas Metálicas / Ferro Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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