Invasive Curvularia Infection in Pediatric Patients With Hematologic Malignancy Identified by Fungal Sequencing.
J Pediatric Infect Dis Soc
; 8(1): 87-91, 2019 Mar 28.
Article
em En
| MEDLINE
| ID: mdl-30265347
ABSTRACT
Curvularia is a saprophytic dematiaceous mold and a rare human pathogen. Here, we report three severely immunocompromised pediatric patients who developed invasive Curvularia infection. Diagnosis was achieved or confirmed in all cases by fungal ribosome sequencing, which hastened species identification and targeted treatment for the patients reported. There are no treatment guidelines for invasive Curvularia infection, though we report three patients who were cured of their infection through a combination of surgical resection and various anti-fungal therapies, indicating a relatively low virulence and good prognosis in comparison to other angioinvasive molds.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ascomicetos
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Leucemia-Linfoma Linfoblástico de Células Precursoras B
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Hospedeiro Imunocomprometido
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Dermatomicoses
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Leucemia-Linfoma Linfoblástico de Células Precursoras
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Leucemia-Linfoma Linfoblástico de Células T Precursoras
Tipo de estudo:
Diagnostic_studies
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Guideline
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Prognostic_studies
Limite:
Child
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Female
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Humans
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Male
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article