Poly(ADP-ribose) polymerase 1 (PARP1) promotes oxidative stress-induced association of Cockayne syndrome group B protein with chromatin.

Boetefuer, Erica L; Lake, Robert J; Dreval, Kostiantyn; Fan, Hua-Ying

Boetefuer, Erica L; Lake, Robert J; Dreval, Kostiantyn; Fan, Hua-Ying.

Afiliação

Boetefuer EL; From the Department of Internal Medicine, Division of Molecular Medicine, Program in Cancer Genetics, Epigenetics, and Genomics, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico 87131; Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Lake RJ; From the Department of Internal Medicine, Division of Molecular Medicine, Program in Cancer Genetics, Epigenetics, and Genomics, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico 87131.
Dreval K; From the Department of Internal Medicine, Division of Molecular Medicine, Program in Cancer Genetics, Epigenetics, and Genomics, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico 87131.
Fan HY; From the Department of Internal Medicine, Division of Molecular Medicine, Program in Cancer Genetics, Epigenetics, and Genomics, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico 87131. Electronic address: hufan@salud.unm.edu.

J Biol Chem ; 293(46): 17863-17874, 2018 11 16.

Article em En | MEDLINE | ID: mdl-30266807

Assuntos

Cromatina/metabolismo; DNA Helicases/metabolismo; Enzimas Reparadoras do DNA/metabolismo; DNA/metabolismo; Estresse Oxidativo/fisiologia; Poli(ADP-Ribose) Polimerase-1/metabolismo; Proteínas de Ligação a Poli-ADP-Ribose/metabolismo; Fator de Ligação a CCCTC/metabolismo; DNA/efeitos da radiação; Dano ao DNA; DNA Helicases/genética; Enzimas Reparadoras do DNA/genética; Loci Gênicos; Humanos; Mutação; Proteínas de Ligação a Poli-ADP-Ribose/genética; Ligação Proteica; Raios Ultravioleta; Vitamina K 3/farmacologia

Palavras-chave

ATP-dependent chromatin remodeling; CSB; Cockayne syndrome protein; DNA repair; PARP1; base-excision repair (BER); chromatin; oxidative stress; reactive oxygen species (ROS); single-strand DNA repair; transcription regulation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Cromatina / DNA Helicases / Estresse Oxidativo / Enzimas Reparadoras do DNA / Poli(ADP-Ribose) Polimerase-1 / Proteínas de Ligação a Poli-ADP-Ribose Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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