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Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-ß production by mediating H3K79me2/3 methylation in macrophages.
Chen, Xiang; Liu, Xingguang; Zhang, Yunkai; Huai, Wanwan; Zhou, Qingqing; Xu, Sheng; Chen, Xi; Li, Nan; Cao, Xuetao.
Afiliação
  • Chen X; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
  • Liu X; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
  • Zhang Y; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
  • Huai W; Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Zhou Q; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
  • Xu S; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
  • Chen X; Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Li N; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China.
  • Cao X; National Key Laboratory of Medical Immunology & Institute of Immunology, Second Military Medical University, Shanghai, 200433, China. caoxt@immunol.org.
Cell Mol Immunol ; 17(1): 76-84, 2020 01.
Article em En | MEDLINE | ID: mdl-30275539

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Histona-Lisina N-Metiltransferase / Interleucina-6 / Interferon beta / Imunidade Inata / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Histona-Lisina N-Metiltransferase / Interleucina-6 / Interferon beta / Imunidade Inata / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article