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iNOS promotes CD24+CD133+ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway.
Wang, Ronghua; Li, Yawen; Tsung, Allan; Huang, Hai; Du, Qiang; Yang, Muqing; Deng, Meihong; Xiong, Si; Wang, Xiju; Zhang, Liyong; Geller, David A; Cheng, Bin; Billiar, Timothy R.
Afiliação
  • Wang R; Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Li Y; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Tsung A; Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Huang H; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Du Q; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Yang M; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Deng M; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Xiong S; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Wang X; Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Zhang L; Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • Geller DA; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Cheng B; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Billiar TR; Department of Gastroenterology and Hepatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; b.cheng@tjh.tjmu.edu.cn billiartr@upmc.edu.
Proc Natl Acad Sci U S A ; 115(43): E10127-E10136, 2018 10 23.
Article em En | MEDLINE | ID: mdl-30297396
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Óxido Nítrico Sintase Tipo II / Antígeno CD24 / Receptores Notch / Proteína ADAM17 / Antígeno AC133 / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Óxido Nítrico Sintase Tipo II / Antígeno CD24 / Receptores Notch / Proteína ADAM17 / Antígeno AC133 / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article