The intact nephron hypothesis as a model for renal drug handling.

Pradhan, Sudeep; Duffull, Stephen B; Walker, Robert J; Wright, Daniel F B

Pradhan, Sudeep; Duffull, Stephen B; Walker, Robert J; Wright, Daniel F B.

Afiliação

Pradhan S; School of Pharmacy, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
Duffull SB; School of Pharmacy, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
Walker RJ; Department of Medicine, University of Otago, Dunedin, New Zealand.
Wright DFB; School of Pharmacy, University of Otago, PO Box 56, Dunedin, 9054, New Zealand. dan.wright@otago.ac.nz.

Eur J Clin Pharmacol ; 75(2): 147-156, 2019 Feb.

Article em En | MEDLINE | ID: mdl-30298363

Assuntos

Néfrons/metabolismo; Preparações Farmacêuticas/metabolismo; Animais; Transporte Biológico/fisiologia; Taxa de Filtração Glomerular/fisiologia; Humanos; Nefropatias/metabolismo; Testes de Função Renal/métodos; Taxa de Depuração Metabólica/fisiologia

Palavras-chave

Intact nephron hypothesis; Renal dose adjustment; Renal drug handling; Systematic review

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Néfrons Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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