Brg1 trans-activates endothelium-derived colony stimulating factor to promote calcium chloride induced abdominal aortic aneurysm in mice.

Zhang, Xinjian; Liu, Shuai; Weng, Xinyu; Wu, Teng; Yu, Liming; Xu, Yong; Guo, Junli

Zhang, Xinjian; Liu, Shuai; Weng, Xinyu; Wu, Teng; Yu, Liming; Xu, Yong; Guo, Junli.

Afiliação

Zhang X; Key Laboratory of Targeted Intervention of Cardiovascular Disease and Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Liu S; Cardiovascular Disease and Research Institute, Affiliated Hospital of Hainan Medical College, Haikou, China.
Weng X; Institute of Biomedical Science, Fudan University, Shanghai, China.
Wu T; Key Laboratory of Targeted Intervention of Cardiovascular Disease and Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Yu L; Key Laboratory of Targeted Intervention of Cardiovascular Disease and Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Department of Pathophysiology, Nanjing Medical University, Nanjing, China.
Xu Y; Key Laboratory of Targeted Intervention of Cardiovascular Disease and Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Department of Pathophysiology, Nanjing Medical University, Nanjing, China; Institute of Biomedical Research, Liaocheng University, Liaocheng, China
Guo J; Cardiovascular Disease and Research Institute, Affiliated Hospital of Hainan Medical College, Haikou, China. Electronic address: guojl0511@126.com.

J Mol Cell Cardiol ; 125: 6-17, 2018 12.

Article em En | MEDLINE | ID: mdl-30336142

Assuntos

Aneurisma da Aorta Abdominal/induzido quimicamente; Aneurisma da Aorta Abdominal/metabolismo; Cloreto de Cálcio/toxicidade; DNA Helicases/metabolismo; Endotélio/metabolismo; Proteínas Nucleares/metabolismo; Fatores de Transcrição/metabolismo; Animais; Movimento Celular/efeitos dos fármacos; Imunoprecipitação da Cromatina; Fatores Estimuladores de Colônias; DNA Helicases/genética; Feminino; Fator Estimulador de Colônias de Macrófagos; Masculino; Camundongos; Camundongos Knockout; Proteínas Nucleares/genética; Reação em Cadeia da Polimerase em Tempo Real; Fatores de Transcrição/genética

Palavras-chave

Abdominal aortic aneurysm; Brg1; Epigenetics; Transcriptional regulation; Vascular endothelial cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Cloreto de Cálcio / Proteínas Nucleares / Aneurisma da Aorta Abdominal / DNA Helicases / Endotélio Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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