Your browser doesn't support javascript.
loading
Pharmacological activities of antroquinonol- Mini review.
Angamuthu, Venkatachalam; Shanmugavadivu, M; Nagarajan, G; Velmurugan, Bharath Kumar.
Afiliação
  • Angamuthu V; Department of Supramolecular Chemistry and Catalysis, Shanghai University, PR China.
  • Shanmugavadivu M; Department of Biotechnology, Dr. N. G. P. Arts and Science College, Coimbatore, India.
  • Nagarajan G; Faculty of Biology, Preparatory Year Deanship, King Faisal University, Al Hofuf, Saudi Arabia.
  • Velmurugan BK; Toxicology and Biomedicine Research Group, Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam. Electronic address: bharath.kumar.velmurugan@tdtu.edu.vn.
Chem Biol Interact ; 297: 8-15, 2019 Jan 05.
Article em En | MEDLINE | ID: mdl-30343039
ABSTRACT
Antrodia camphorata is an expensive mushroom that grows on the inner cavity of an endangered native tree of Taiwan namely Cinnamomum kanehirai Hayata. It is used as a traditional medicine in Taiwan and has several health benefits including free radical scavenging, anti-inflammatory, antimicrobial, hepatoprotective, neuroprotective, antidiabetic, and free radical-induced DNA damage protecting activities. Antroquinonol is a tetrahydro ubiquinone derivative found predominately in the mycelium of Antrodia camphorata, and is characterized by numerous biological and pharmacological activities. Several studies have revealed potential anticancer effects of antroquinonol in various carcinogenic models. Moreover, a phase II clinical trial is ongoing in the US and Taiwan to treat the lung cancer patients with this active compound. The present review aims at depicting a detailed view of the synthetic procedures of antroquinonol as well as deciphering its potential health benefits with a special emphasis on anticancer properties.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ubiquinona / Antrodia / Neoplasias Pulmonares / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ubiquinona / Antrodia / Neoplasias Pulmonares / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article