Optimized protocol for induction of cytochrome P450 enzymes 1A2 and 3A4 in human primary-like hepatocyte cell strain HepaFH3 to study in vitro toxicology.

Kammerer, Sarah; Küpper, Jan-Heiner

Kammerer, Sarah; Küpper, Jan-Heiner.

Afiliação

Kammerer S; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Germany.
Küpper JH; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Germany.

Clin Hemorheol Microcirc ; 70(4): 563-571, 2018.

Article em En | MEDLINE | ID: mdl-30347615

Assuntos

Citocromo P-450 CYP1A2/metabolismo; Hepatócitos/metabolismo; Células Cultivadas; Humanos

Palavras-chave

CYP induction; Cytochrome P450; DILI; HepaFH3; drug induced liver injury; liver in vitro model; liver toxicity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citocromo P-450 CYP1A2 / Hepatócitos Tipo de estudo: Guideline Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google