Decitabine Induced Delayed Cardiomyopathy in Hematologic Malignancy.

Agasthi, Pradyumna; Narayanasamy, Hemalatha; Sorajja, Dan; Slack, James; Mookadam, Farouk.

Afiliação

Agasthi P; Department of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USA.
Narayanasamy H; Department of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USA.
Sorajja D; Department of Cardiovascular Diseases, Mayo Clinic, Arizona 85259, USA.
Slack J; Department of Cardio-Oncology, Mayo Clinic, Arizona 85259, USA.
Mookadam F; Department of Internal Medicine, Mayo Clinic, Arizona 85259, USA.

Case Rep Cardiol ; 2018: 3953579, 2018.

Article em En | MEDLINE | ID: mdl-30363961

ABSTRACT

Decitabine is a pyrimidine analogue of nucleoside cytidine, used for the treatment of myelodysplastic syndromes, chronic myelogenous leukemia, and acute myelogenous leukemia. We present a case of cardiomyopathy associated with decitabine used for secondary acute myelogenous leukemia. The patient presented with new heart failure symptoms and an ejection fraction decline.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article