ß-1,3-glucan-lacking <i>Aspergillus fumigatus</i> mediates an efficient antifungal immune response by activating complement and dendritic cells.

Steger, Marion; Bermejo-Jambrina, Marta; Yordanov, Teodor; Wagener, Johannes; Brakhage, Axel A; Pittl, Verena; Huber, Lukas A; Haas, Hubertus; Lass-Flörl, Cornelia; Posch, Wilfried; Wilflingseder, Doris

ß-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells.

Steger, Marion; Bermejo-Jambrina, Marta; Yordanov, Teodor; Wagener, Johannes; Brakhage, Axel A; Pittl, Verena; Huber, Lukas A; Haas, Hubertus; Lass-Flörl, Cornelia; Posch, Wilfried; Wilflingseder, Doris.

Afiliação

Steger M; Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Bermejo-Jambrina M; Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Yordanov T; Division of Cell Biology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.
Wagener J; Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Munich, Germany.
Brakhage AA; Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Germany.
Pittl V; Division of Molecular Biology, Medical University Innsbruck, Innsbruck, Austria.
Huber LA; Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Haas H; Division of Cell Biology, Biocenter, Innsbruck Medical University, Innsbruck, Austria.
Lass-Flörl C; Department of Microbiology and Molecular Biology, Friedrich Schiller University (FSU), Jena, Germany.
Posch W; Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
Wilflingseder D; Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.

Virulence ; 10(1): 957-969, 2019 12.

Article em En | MEDLINE | ID: mdl-30372658

Assuntos

Aspergillus fumigatus/química; Aspergillus fumigatus/imunologia; Ativação do Complemento; Células Dendríticas/imunologia; beta-Glucanas; Aspergilose/microbiologia; Aspergillus fumigatus/genética; Citocinas/imunologia; Equinocandinas/uso terapêutico; Humanos; Imunidade Inata; Mutação; Esporos Fúngicos/imunologia; Células THP-1

Palavras-chave

3-glucan; Fungal infection; T helper cells; complement; dendritic cell; ß-1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergillus fumigatus / Células Dendríticas / Ativação do Complemento / Beta-Glucanas Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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