Recent Syntheses and Strategies toward Polycyclic Gelsemium Alkaloids.
Angew Chem Int Ed Engl
; 58(3): 681-694, 2019 01 14.
Article
em En
| MEDLINE
| ID: mdl-30378226
ABSTRACT
This Minireview is focused on an in-depth discussion of comparative strategies to construct the gelsemine and gelsedine classes of the gelsemium alkaloids. This document highlights the diversity of strategies used to access specific motifs found within these targets a)â
the fused "[3.2.1]bicycle" (in gelsemine) and "oxabicycle" (in gelsedine class); b)â
the "piroxindole" moiety with C7 quaternary center; c)â
the "N-heterocycles" and d)â
the "THP" moiety with C20 quaternary center (in gelsemine).
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos Policíclicos
/
Gelsemium
/
Alcaloides
/
Técnicas de Química Sintética
/
Oxindóis
Tipo de estudo:
Qualitative_research
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article